While both medications help with weight management, they are distinct chemical compounds with different half-lives and receptor affinities
GI side effects like nausea and diarrhea were most common, but these were manageable and resolved over time, researchers said.No increase in serious adverse events or severe low blood sugar was seen with the higher dose.The greater magnitudes of bodyweight reduction seen in this trial, as well as the improvements in cardiovascular risk factors and glucose control, can have beneficial effects on health goals in clinical practice, researchers concluded.However, they noted that further research is needed to fully understand the long-term benefits and risks of a tripled semaglutide dose taken regularly.Novo Nordisk, the maker of semaglutide, sponsored both clinical trials.More informationThe University of California-Davis has more on semaglutide for weight loss.SOURCES: The Lancet, news release, Sept

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They tend to crave more protein-rich foods, so a shift toward higher quality foods may contribute not only to their weight loss but to a lower risk in cancer, she says
MRI image analysis All patients underwent abdominal MRI measurements before and after the treatment
These medications operating within established GLP-1 mechanisms allow flexibility for people preferring a pill form